New Commentary on the PDS Metric

We have posted a short commentary on Arxiv that examines the behavior of the PDS evaluation metric used in the Virtual Cell Challenge:

👉 arXiv:2511.16954

The note discusses why early improvements in PDS can be unexpectedly difficult to achieve, and how scaling can lead to significant gains by making the usual ℓ₁/ℓ₂-based PDS behave more like a cosine-similarity–based score, which is often more discriminative.

We hope this analysis may be helpful for researchers who are studying the metric or developing methods designed to perform well under PDS.

Jingshu Wang
Jingshu Wang
Assistant Professor in Statistics

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