Mendelian Randomization

Preprint: Improving Estimation Efficiencies for Family-Based GWAS by Integrating Large External Data

A new calibration method to boost efficiency and power in family-based GWAS using external summary statistics.

FLOW-MR Published in Nature Communications

Our work on causal mediation analysis for time-varying heritable risk factors using Mendelian Randomization is now published in Nature Communications.

GRAPPLE

An R package for Mendelian Randomization (MR), which features the detection of mutliple pleiotropic pathways, the direction of causation and multivariate MR. [Paper](https://jingshuw.org/publication/wang-2020-aa/)

MR.RAPS

An R package for two-sample summary data Mendelian Randomization (MR) using the robust adjusted profile score. [Paper](https://jingshuw.org/publication/zhao-2020-aa/)